Based or created in MN (M-N)
- Magnepan (White Bear Lake) - makes speakers for audiophiles
- magnetic poetry (Minneapolis) - writer's block turns into entrepeneurial gold; check your fridge
- Malt-O-Meal (Northfield) - roots as a hot wheat cereal company in 1919
- Manhattan Group (Minneapolis) - toy maker of the popular Groovy Girls
- Mariner Software (Minneapolis) - produces alternatives to Microsoft Office for the Mac platform
- Mar-O-Bar Company (Minneapolis) - started in 1920 and introduced the Milky Way chocolate bar in 1923. See Frank Mars
- Masking Tape (St. Paul) - 3M engineer Richard Drew invented it in 1925.
- McKnight Foundation (Minneapolis) - one of the largest American philanthropic foundations
- Medtronic (Fridley) - world's largest company in medical technology
- Minnesota Multiphasic Personality Inventory (MMPI) (Minneapolis) - widely used test of adult psychopathology
- Minnesota Public Radio (St. Paul) - largest producer of national public radio programs
- Minnetonka Moccasin (Minneapolis) - the private footwear company began in 1946; most popular style is the Thunderbird
- MoneyGram (St. Louis Park) - Travelers Expresss, founded in 1940, bought the 2nd largest money transfer in the world in 1998 and renamed itself in 2005
- Music Go Round (Minneapolis) - franchise for used musical instruments. See Winmark
- Musicland Group (Minnetonka) - owns Sam Goody, Suncoast and MediaPlay stores
- Mystery Science Theater 3000 (Eden Prairie) - the tv show on Minnesota's public access channel became a cult hit
- Nada-Chair (St. Paul) - makes back-supporting slings for sitting
- National Arbitration Forum (Minneapolis) - alternative dispute resolution provider
- Nobel Peace Prize Forum (various) - an annual collegiate event with cooperation from the Norweigan Nobel Institute
- Nordic Track (Excelsior) - inventor Ed Pauls filed for a patent in the mid 70s
- Northwest Airlines (Bloomington) - first major airline to ban smoking on international flights
- Nutrisoda (Minneapolis) - a line of nutrient-infused sodas from Ardea Beverage Co.