Based or created in MN (E-F)
- Eckankar (Chanhassen) - new religious movement; some call it a cult
- Ecolab (St. Paul) - commercial cleaning and sanitizing since 1923
- Fair Isaac (Minneapolis) - developed FICO, one of the most used credit scoring measures
- Famous Dave's (Minnetonka) - chain of BBQ restaurants in almost 30 states
- Fingerhut (Minnetonka) - once the country's second largest catalog retailer
- Ford Ranger trucks (St. Paul) - a plant by the Mississippi River assembled them